Highway Patrol is investigating deadly crash in Audrain County

COLUMBIA, Mo. (KMIZ)
Emergency crews are on the scene of a deadly crash in Audrain County Wednesday morning involving two semi-trucks and an SUV.
According to a social media post from the Missouri State Highway Patrol, troopers are investigating a three-vehicle crash on Missouri Highway 22 near Audrain Road 215.
The roadway is blocked, and troopers are asking people to avoid the area.
🚨Fatal Crash in Audrain County🚨
— MSHP Troop F (@MSHPTrooperF) January 21, 2026
Troopers are investigating a three vehicle crash on MO 22, near Audrain Road 215 (between Centralia and Thompson).
The crash involves two tractor trailers and one SUV.
The roadway is blocked. Please avoid the area and use an alternate route. pic.twitter.com/sJ7Kfh3su1
According to the Audrain County Sheriff's Department, they have no additional information at this time. The MSHP is conducting the investigation.
ABC 17 crews on scene saw an MU Healthcare helicopter, two overturned semi-trucks and a severely damaged car in Audrain County. The Missouri State Highway Patrol, Audrain Ambulance District and a Boone Health ambulance are on scene.
One of the overturned trucks does have an Amren logo.
This is a developing story.
